| Champion |
Louisville Lady Sluggers 18u
(20-9-1 in 2021)
|
18B
|
Moscow Mills, MO
|
| Runner-Up |
Midland Bandits Franzen/Reynolds
(20-11-4 in 2021)
National Qualified
State Qualified
|
18B
|
Saint Peters, MO
|
| Third Place |
St Louis Heat 05
(6-10-1 in 2021)
|
16A
|
Ballwin, MO
|
| |
Aftermath Fastpitch
(14-11-1 in 2021)
|
18B
|
Foristell, MO
|
| |
Cyclones
(16-27-0 in 2021)
|
18B
|
Imperial, MO
|
| |
Missouri Storm
(2-4-2 in 2021)
|
18B
|
Warrenton, MO
|
| |
STL Blaze Softball
(1-4-0 in 2021)
|
18C
|
Kirkwood, MO
|